Physician · Scientist · Entrepreneur · Strategist
Board-certified OB-GYN (FACOG) and physician-scientist with an MD, PhD in Reproductive Physiology, and an Executive MBA — one of fewer than 1% of US physicians holding all three degrees simultaneously. Medical Director at a top-10 global pharmaceutical company, NIH-funded clinical researcher, and founder of a pre-revenue medical device company raising institutional capital. Over 13 peer-reviewed publications, 20+ conference abstracts, and 31+ scientific presentations spanning gynecologic oncology, translational medicine, and women's health.
Professional Experience
Founder & CEO
2026 – Present
NEG+ Innovations, Inc. — Delaware C-Corp · Weston, MA
- Developing 3-device women's health portfolio: Belotte Colpotomizer™, POP-Q AutoSense™, Pudendal Nerve Block Device™ — combined US TAM $400M+
- Raising seed capital via Post-Money SAFE; co-investing personally on identical terms; targeting institutional Series Seed from medtech-focused venture investors
- 4 provisional patents filed; 8-member advisory board including former FDA Principal Deputy Commissioner
- Pursuing NIH STTR (NICHD/NIBIB) and NSF STTR non-dilutive funding parallel to private capital raise
Medical Director, Oncology Clinical Development
Present
GlaxoSmithKline (GSK) · Boston–Waltham–Cambridge, MA
- Late-stage clinical programs in gynecologic oncology; named investigator on OPAL trial (niraparib neoadjuvant, Trials 2024) and OVARIO Phase II (Gynecologic Oncology 2022)
- Protocol strategy, safety review, regulatory submission, and scientific communication across Phase 1/2 oncology programs including POLQi (GSK4524101) — JCO abstract 2025
- Inclusion & Diversity Champion, GSK Oncology — Boston–Waltham–Cambridge region
Founder & Medical Director
Sept 2023 – Present
New England Gynecology Plus PLLC (NEG+) · Weston, MA
Patient-centered women's health practice; evidence-based non-obstetrical gynecologic care including telehealth; clinical operations for device validation studies. Six pillars: clinical care, R&D, education, consulting, community engagement, innovation.
Clinical Associate Professor, OB/GYN & Women's Health
Prior
Albert Einstein College of Medicine / Montefiore · Bronx, NY
Grand Rounds lecturer; mentorship of residents; invited research lecture on cisplatin resistance (Dept. OB/GYN, 2017). Dual affiliation with Karmanos Cancer Institute and Wayne State University School of Medicine.
NIH WRHR Scholar & Laboratory Researcher
During Residency/PhD
Wayne State University / Karmanos Cancer Institute · Detroit, MI
NIH T32 Women's Reproductive Health Research Scholar. PhD research: oxidative stress mechanisms in cisplatin chemoresistance — epithelial ovarian cancer. Produced 8 original research publications; 15+ refereed conference presentations at AACR, SGO, ASRM, AAGL.
Felix Rutledge Fellow in Gynecologic Oncology
2010
MD Anderson Cancer Center · Houston, TX
Competitive fellowship at the world's leading cancer center. Invited lecture: "Management of Bowel Obstruction in the Setting of Ovarian Cancer."
Research & Scholarship
13
Peer-Reviewed Publications
20
Published Abstracts
31+
Presentations & Lectures
3
Ad-Hoc Reviewer Journals
4+
Patents Pending
Landmark Publications
Belotte J et al. OPAL trial: niraparib vs. platinum-taxane neoadjuvant in HRD ovarian cancer. Trials. 2024;25(1):301. PMID: 38702828.
Hardesty MM, ... Belotte J et al. OVARIO Phase II — niraparib + bevacizumab maintenance in advanced ovarian cancer. Gynecol Oncol. 2022. PMID: 35690498. IF: 5.3.
Belotte J et al. Oxidative stress and cisplatin resistance in epithelial ovarian cancer. Reproductive Sciences. 2014;21(4):503–8. PMID: 24077440. Cited ×7.
Belotte J et al. Catalase SNP strongly associated with ovarian cancer survival. PLOS ONE. 2015;10(8):e0135739. PMID: 26301412.
Education & Training
Executive MBA for Physicians
Completed
Heller School · Brandeis University, Waltham MA
PhD — Reproductive Physiology
Completed
Wayne State University, Detroit MI
Residency — Obstetrics & Gynecology
Completed
Wayne State Univ. / Detroit Medical Center
Doctor of Medicine (MD)
Completed
Université Notre Dame d'Haïti
Leadership & Service
President-Elect · Rotary Club of Weston & Wayland
2025
District 7910 Polio Plus Chair · Rotary International
Elected Board Member
Wayne County Medical Society of Southeast Michigan
I&D Champion — Oncology Division
GlaxoSmithKline · Boston–Waltham–Cambridge
International Keynote Speaker
AMHE 45th Annual Convention · Cartagena, Colombia · 2018